Mesenchymal Stem CellsAngie Godinez
Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, and potentially, other cell types. For years, it has been clear that MSCs are a leading type of stem cell being investigated for therapeutic applications, because they have the potential to treat a wide range of acute and degenerative diseases.
In addition to secreting factors that can stimulate tissue repair, MSCs can substantially alter their microenvironment, exerting effects that are both anti-inflammatory and anti-fibrotic.
MSCs are also advantageous over other stem cells types, because they avoid the ethical issues that surround embryonic stem cell research and appear to be immuno-privileged. Importantly, MSCs also well-suited for use in the exponential growth area of 3D printing, because of their unusual capacity to form structural tissues.
To date, there have been more than 30,000 scientific publications published about the cell type and there are now nearly 500 MSC clinical trials underway worldwide, with East Asia, Europe, and the United States representing hot-spots for clinical trial activity.
Furthermore, mesenchymal stem cells surpassed hematopoietic stem cells to become the most common stem cell type to appear within the scientific literature in 2015. MSCs were also the only stem cell type that had an increase in scientific publications from 2014 to 2015.
Google Trend data also shows MSC searches to be approximately twice as common as the next most common adult stem cell type.
Therefore, a global strategic report describes the current status of MSC research, ongoing clinical trials involving MSCs, late stage MSC clinical trials, and possible uses of MSCs in cell therapy. Because MSCs are a sub-segment of the broader cell therapy (CT) and regenerative medicine (RM) markets, it gives an overview of the regenerative medicine industry and overall cell therapy industry.
It also explores recent advances in MSC products and technologies, identifies research priorities by market segment, and assesses 35 leading competitors within the MSC marketplace.
For pharmaceutical companies, it reveals how advances in MSC research can reveal potential new drug targets, improve methods of drug delivery, and provide personalized treatment strategies.
The mesenchymal stem cell market is important because:
1) Mesenchymal stem cells (MSCs) are one of the fastest growing areas of stem cell research
2) MSCs are now more frequently cited than any other stem cell type within the scientific literature
3) Google Trend data shows MSC searches to be approximately twice as common as the next most common adult stem cell type